Anti-hyperglycaemic activity of H. rosa-sinensis leaves is partly mediated by inhibition of carbohydrate digestion and absorption, and enhancement of insulin secretion
ConclusionThese data suggest the antihyperglycaemic activity of HRS is mediated by inhibiting carbohydrate digestion and absorption, while significantly enhancing insulin secretion in a dose dependent manner. This suggests that HRS has potential as a novel antidiabetic therapy or a dietary supplement for the treatment of type 2 diabetes.Graphical abstract
Consider COVID-19 in patients presenting with what looks like a typical cardiac syndrome, even in the absence of fever or cough, advise New York City-based cardiologists.Medscape Medical News
Conclusion. In this consecutive case series we performed 231 ADRs in 147 patients in the outpatient setting, including multilevel and revision procedures, with 2 minor postoperative complications resulting in hospital unplanned admissions within 90 days. We believe that these procedures are safe to perform in an ASC. An efficient surgical team and careful patient selection criteria are critical in making this possible. Level of Evidence: 3
Conclusion. Spinal infection in the presence of liver cirrhosis is challenging. The rate epidural abscess formation is relatively high. Early diagnosis remains the main cornerstone in the management and the indication for surgery should be carefully considered. Minimally invasive techniques should be used when possible to minimize complication rate, and higher amounts of intraoperative blood loss should be expected. Level of Evidence: 4
In this study, we examined the PPARγ expression and the protective effects of pioglitazone after transient forebrain ischemia. We focused on Akt and signal transducers and activators of transcription 3 (STAT3), key pathways of prosurvival signaling in ischemic neuronal injury as the mechanisms of pioglitazone’s effects. Male Sprague–Dawley rats were given daily oral administration of pioglitazone (0.2, 2 and 20 mg/kg/d) or the vehicle, and transient forebrain ischemia was induced by 5-minute occlusion of bilateral common carotid arteries with hypotension. Western blot and immunohistochemistry revealed tha...
In Conscious Growth Club, there was a recent discussion about finding cuddle partners – i.e. someone to physically cuddle with when you want – so I thought I’d turn what I shared about this into a blog post with some tips on finding cuddle partners. Obviously this will be more useful when you’re not under a virus lockdown. 😉 Basically what I shared in CGC was a list of tips for increasing the chances of finding a cuddle partner. Here’s a refined version of that: Hang out with cuddle-friendly and touch-friendly people more often. Spend more time around the hugger types. This helps a lo...
One would hope that it does not require an ongoing pandemic and related hysteria to point out that old people have poorly functioning immune systems, and thus suffer disproportionately the burden of infectious disease. But perhaps it does. The 2017-2018 seasonal influenza, a modestly more severe occurrence of something that happens every year, killed something like 60,000 people in the US alone, with little notice or comment. There is nothing so terrible that it won't be accepted - ignored, even - if it is normal. Floodgates of funding for infectious disease research and development have been opened in response to C...
Publication date: Available online 6 April 2020Source: Molecular MetabolismAuthor(s): Naotoshi Wada, Hiroyuki Yamada, Shinichiro Motoyama, Makoto Saburi, Takeshi Sugimoto, Hiroshi Kubota, Daisuke Miyawaki, Noriyuki Wakana, Daisuke Kami, Takehiro Ogata, Satoaki Matoba
TYPE 2 diabetes is a chronic condition that can be a precursor to more serious health problems so it is imperative to keep the condition in check. Lowering blood sugar levels helps to stabilise the condition and a particular cooking oil has been shown to facilitate this process.
Living with type 1 diabetes and having trouble sleeping? DiabetesMine has some ideas to help.
Whether or not the mortality finding is real, one expert says, in any case, levothyroxine doesn't make older patients with subclinical hypothyroidism feel any better, so is unwarranted.Medscape Medical News