Synergistic Combination of Oncolytic Virotherapy and Immunotherapy for Glioma.
CONCLUSIONS: IL15Rα-IL15-armed oncolytic poxviruses provide potent antitumor effects against brain tumors when combined with adoptive T cell therapy, rapamycin and celecoxib. PMID: 32019860 [PubMed - as supplied by publisher]
Publication date: Available online 30 March 2020Source: Academic RadiologyAuthor(s): Hongdan Zhang, Li Xu, Zhiping Zhong, Yupin Liu, Yu Long, Shuqin Zhou
Publication date: Available online 31 March 2020Source: Aggression and Violent BehaviorAuthor(s): Ashleigh Lupton, Huda Abu-Suwa, Glen C. Bolton, Charles Golden
Most women who are notified by mail that they have a high risk of breast cancer are unlikely to do anything about it, a small study suggests.Reuters Health Information
ConclusionsOur study reveals the need for targeted patient ‐education about the benefits and limitations of follow‐up. In order to meet increasing costs of cancer care, individualized follow‐up procedures adjusted to risk of recurrence and late‐effects in cervical cancer survivors are warranted.
Radiation therapy vendor Varian Medical Systems has added new artificial intelligence...Read more on AuntMinnie.comRelated Reading: Varian gets FDA nod for Ethos adaptive therapy unit Varian posts strong Q1 sales growth as profit slips Varian installs systems in Africa, U.S. Varian awarded Mich. cancer software contract Varian posts continued revenue gains in Q4, fiscal 2019
The Department of Health and Human Services outlined support for Moderna and Johnson &Johnson, as the companies work to develop coronavirus vaccines. Beefing up manufacturing capacity is a priority.(Image credit: David L. Ryan/Boston Globe via Getty Images)
ConclusionsAlthough her main symptoms were compatible with NMDARE, MRI findings were more compatible with NMOSD. Therefore, we interpreted her clinical and imaging features as a mixed phenotype of NMOSD and NMDARE. This case report provides additional evidence that double positivity for AQP4 ‐ab and NMDAR‐ab is associated with a mixed phenotype of NMOSD and NMDARE.
AbstractNeuropathic pain (NeP) is an intractable pain caused by a lesion or disease of the somatosensory nervous system. NeP is often challenging to manage because most of the mechanisms remain to be elucidated. Recent investigations in the field of autoimmune neurology have demonstrated that specific autoantibodies against antigens in the somatosensory pathway can cause NeP. Detection of pathogenic autoantibodies in NeP adds to the understanding of the mechanism of pain, which might aid in the development of novel immunotherapies. Therefore, it is necessary to explore novel NeP ‐related autoantibodies to improve the man...
Israel has begun testing a COVID-19 vaccine prototype on rodents at its bio-chemical defense laboratory, a source said on Tuesday.
We’re tackling a few urgent questions from parents in this time of coronavirus and COVID-19. Are you wondering if babies and children should continue to have vaccines on schedule? Thinking about how to manage regular medical appointments, and which situations require in-person visits to a pediatric practice? Read on. Should parents take babies for initial vaccines right now? What about toddlers and older children who are due for vaccines? The answer to this question is going to depend on many factors, including what your doctor’s office is offering. As with all health care decisions, it comes down to weighing r...