The narrative paradox of the BRCA gene: an ethnographic study in the clinical encounters of ovarian cancer patients.

The narrative paradox of the BRCA gene: an ethnographic study in the clinical encounters of ovarian cancer patients. Anthropol Med. 2020 Feb 03;:1-16 Authors: Therond C, Lanceley A, Gibbon S, Rahman B Abstract In this era of personalisation a patient's molecular profile plays an increasingly central role in development and delivery of personalised medicine. This paper sets out to explore the sociocultural implications of mainstreaming BRCA genetic testing in the treatment of advanced ovarian cancer patients, who carry a BRCA1 or BRCA2 gene mutation. It draws on ethnographic research conducted by between April-June 2016 in a large tertiary London hospital. Participant observation was conducted across two sites. For the first two weeks participant observation was conducted in the traditional genetic testing setting in two separate clinics. From thereon, participant observation was conducted in the clinical encounters of treating patients in the ovarian cancer clinic. In addition, face-to-face interviews were conducted with medical oncologists who worked in the clinic. Contributing to the fields of cancer genetics, personalised medicine and medical material culture studies in medical anthropology the paper seeks to further discussions about the interactions and relationships unfolding between medical objects and subjects across the landscape of cancer care. It highlights the importance of clinic-based ethnography to examine the complexi...
Source: Anthropology and Medicine - Category: International Medicine & Public Health Tags: Anthropol Med Source Type: research