Dosimetric impact of rotational errors on the quality of VMAT-SRS for multiple brain metastases: Comparison between single- and two-isocenter treatment planning techniques.

CONCLUSION: Limiting the lesion-to-isocenter distance to ≤4 cm by introducing additional isocenter(s) appears to partly mitigate severe target underdosage, especially for smaller target sizes. If OAR-sparing is also a concern, more stringent rotational error tolerances apply.
PMID: 32022447 [PubMed - as supplied by publisher]

Source: Journal of Applied Clinical Medical Physics - February 4, 2020 Category: Physics Authors: Prentou G, Pappas EP, Logothetis A, Koutsouveli E, Pantelis E, Papagiannis P, Karaiskos P Tags: J Appl Clin Med Phys Source Type: research