Bone density may not be increased by vitamin supplementation alone

According to a study published in theJournal of Bone and Mineral Research, vitamin D supplementation alone may not improve bone density or strength in adults without vitamin D deficiency.Endocrinology Advisor
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Authors: Gau JT, Ebersbacher C, Kao TC Abstract Context: Subclinical features of zinc deficiency can be challenging to recognize. The prevalence of zinc deficiency based on blood zinc concentration in an adult outpatient clinic setting has not been well-studied. Objective: To estimate the prevalence of low serum zinc concentrations among community-dwelling adults, and to characterize clinical features and risk factors associated with zinc deficiency. Methods: This retrospective pilot prevalence study took place from 2014 to 2017 at an outpatient clinic in southeast Ohio. Patients aged 50 years or older with...
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
Authors: de Souza Freitas R, Fratelli CF, de Souza Silva CM, de Lima LR, Stival MM, da Silva ICR, Schwerz Funghetto S Abstract Aging is accompanied by various functional modifications determined by their environment, lifestyle, nutrition, and genetics. Based on these factors, it is essential to verify the vitamin deficiency in the elderly population. Hypovitaminosis D is commonly present in human aging, increasing the chances of developing noncommunicable chronic diseases. The VDR gene TaqI polymorphism may modify the vitamin D metabolic pathway by altering the interaction between the vitamin D receptor and the act...
Source: Journal of Aging Research - Category: Geriatrics Tags: J Aging Res Source Type: research
We report the case of a 10-year-old Chinese boy complaining of yellowish-brown teeth with extensive caries. Diagnoses: Clinical and laboratory examinations were performed, and VDDR-I was confirmed. Scanning electron microscopy confirmed amelogenesis imperfecta. Interventions: The patient had been taking drugs intervention for VDDR-I from the age of 3 years. The decayed teeth were treated, and metal-preformed crowns were placed to prevent further impairment. Sequence tooth extraction and remineralization therapy were also performed. Outcomes: After 3 years of follow-up, the patient exhibited normal tooth replacemen...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
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Source: Gynecological Endocrinology - Category: Endocrinology Authors: Source Type: research
Purpose of review The present narrative review analyzes emerging research implicating vitamin D status and supplementation with skeletal muscle homeostasis and functions in two distinct segments of the adult population: young athletes and older adults. Recent findings Vitamin D deficiency compromises multiple indices of muscle function in young athletes and older adults. A variety of vitamin D3 (cholecalciferol) supplementation regimens may transition young athletes and older adults from deficient or inadequate to adequate vitamin D status. Vitamin D supplementation, used to treat a vitamin D deficiency, but not neces...
Source: Current Opinion in Clinical Nutrition and Metabolic Care - Category: Nutrition Tags: MICRONUTRIENT SUPPLEMENTATION AND FUNCTIONAL FOODS: Edited by Nathalie M. Delzenne and Henry C. Lukaski Source Type: research
Klotho is one of the few longevity-associated genes with robustly demonstrated effects in both directions: reduce its expression and life span is reduced, increase its expression and life span is increased. Klotho levels decline with age, and this decline is strongly associated with loss of cognitive function, but, interestingly, this may be a very indirect effect that exists due to klotho's influence over kidney function in aging. More klotho implies a slower decline in kidney function, and loss of kidney function is also shown to be a contributing factor in cognitive decline. Thus there is some interest in the research c...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Abstract Vitamin D deficiency (serum 25-hydroxyvitamin D (25(OH)D) concentration
Source: The British Journal of Nutrition - Category: Nutrition Authors: Tags: Br J Nutr Source Type: research
AbstractIntroductionIn pregnancy, vitamin D deficiency is associated with increased risk of fetal growth restriction and preeclampsia. The underlying mechanisms are not known but placental dysfunction is believed to play a role in fetal growth restriction and preeclampsia. In a Danish population, where health authorities recommend a 10 µg/day vitamin D supplement during pregnancy, we explored current use of vitamin D supplements and vitamin D status. In term placentas, alterations in vitamin D metabolism and placental growth evaluated by the key placental growth factor PAPP‐A and their relation to vitamin D insuffi...
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Authors: Wang Z, Peng C, Wang P, Sui J, Wang Y, Sun G, Liu M Abstract BACKGROUND AND AIM: A nonskeletal role of vitamin D in primary biliary cholangitis (PBC) patients is not yet clear. The purpose of this study is to investigate the serum vitamin D level in patients with PBC and to explore whether serum vitamin D level is related to disease progression. METHODS: The serum levels of 25(OH)D3 were measured in 185 PBC patients and 141 healthy controls. The association with vitamin D levels and disease progression, particularly natural course, was assessed. RESULTS: Serum vitamin D levels were measured in 185 ...
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
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