Identifying the Optimal Fractionation Schedules for Improved Response Rates and Survival in Patients with Metastatic Melanoma Treated with Ipilimumab and Radiotherapy

Conclusion: This hypothesis-generating study suggests that patients who cannot receive ablative intent radiotherapy may be more likely to benefit from concurrent radiotherapy with ipilimumab if their fractionation schedule has a BED above 46.5 - 50.9 Gy. Prospective trials evaluating this question should be considered.
Source: Current Cancer Therapy Reviews - Category: Cancer & Oncology Source Type: research