Control of tumor angiogenesis and metastasis through modulation of cell redox state

Publication date: Available online 5 February 2020Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): José J. Serrano, Belén Delgado, Miguel Ángel MedinaAbstractRedox reactions pervade all biology. The control of cellular redox state is essential for bioenergetics and for the proper functioning of many biological functions. This review traces a timeline of findings regarding the connections between redox and cancer. There is ample evidence of the involvement of cellular redox state on the different hallmarks of cancer. Evidence of the control of tumor angiogenesis and metastasis through modulation of cell redox state is reviewed and highlighted.
Source: Biochimica et Biophysica Acta (BBA) Reviews on Cancer - Category: Cancer & Oncology Source Type: research