Intimal sarcoma of pulmonary arteries.
[Intimal sarcoma of pulmonary arteries]. Orv Hetil. 2020 Feb;161(6):232-236 Authors: Sejben A, Tiszlavicz L, Furák J, Boros K, Sápi Z, Zombori T Abstract Pulmonary arterial intimal sarcoma is a rare tumour with high mortality. Due to its localisation, the symptoms can mimic pulmonary thromboembolism and pneumonia, therefore assessing the diagnosis and choosing the adequate therapy is never easy. Its therapy mainly consists of surgery combined with radiochemotherapy. A 46-year-old male patient with testicular seminoma, pulmonary embolism, bronchial asthma and pollen allergy in his history had a follow-up thoracic CT. On the left side of the lung, a pleura-infiltrating 7-8 cm lesion, which occluded the pulmonary artery, was described. The first biopsy specimen showed fragments of spindle cell tumour. The primary diagnosis was leiomyoma, leiomyomatous hyperplasia, yet the presence of leiomyosarcoma could not have been ruled out. Due to the arterial obstruction, the patient underwent left sided pulmonectomy. Histological examination showed a tumour mostly composed of spindle cells that were diffusely positive with SMA, focally diffuse with MDM2 immunohistochemistry together with high proliferation activity. h-Caldesmon, S-100, ERG and pancytokeratin expressions were not detected. With fluorescent in situ hybridization 10% of tumour cells showed polysomy and MDM2 amplification. According to the results, high-grade pulmonary arterial intimal sarc...
ConclusionThe proposed multiparametric MRI-based SLICs+MTh method performs noninvasive assessment of NACT response in osteosarcoma that may improve cancer treatment monitoring, planning, and overall prognosis.Key Points• The simple linear iterative clustering supervoxels and Otsu multithresholding-based technique (SLICs+MTh) successfully estimates the proportion of necrosis, viable tumor, and edema in osteosarcoma in the course of chemotherapy.• The proposed technique is noninvasive and uses multiparametric MRI to measure necrosis as an indication of anticancer treatment response.• SLICs+MTh-based necrosis w...
Authors: López Castro J PMID: 32446683 [PubMed - as supplied by publisher]
HIGH BLOOD PRESSURE may seem harmless but the condition can be a precursor to heart disease so it is important to keep it in check. Nuts have been shown to have a moderating effect on blood pressure and one nut comes out on top.
Publication date: Available online 24 May 2020Source: Annals of Emergency MedicineAuthor(s): Maria A. de Winter, Eline D.P. van Bergen, Paco M.J. Welsing, Adriaan O. Kraaijeveld, Karin H.A. H. Kaasjager, Mathilde Nijkeuter
Cordero, a 41-year-old Tony nominee, was initially hospitalized March 30 after developing pneumonia and later tested positive for the coronavirus.
Publication date: Available online 24 May 2020Source: Canadian Journal of CardiologyAuthor(s): Blake Sandery, Janis M. Dionne
Authors: Urban AE, Cubała WJ Abstract Eugeroics are a relatively new class of wakefulness-promoting agents. Thegroup includes adrafinil, modafinil and armodafinil. Modafinil is the most widely used and the best studied agent. Indications for the use of modafinil include the treatment of narcolepsy, shift-work sleep disorders and excessive daytime sleepiness associated with obstructive sleep apnea. Many studies show the utility of modafinil and armodafinil in the treatment of depression - both in monotherapy andas potentiation therapy if needed. Modafinil has proven to be effective in the treatment of residual symp...
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WOODLAND HILLS, Calif., May 25, 2020 -- (Healthcare Sales &Marketing Network) -- 4DMedical, an Australian medical technology company specializing in medical imaging innovation software, announced today it has received clearance from the U.S. Food &Drug ... Diagnostics, Radiology, FDA 4DMedical, COVID-19, asthma, COPD, cystic fibrosis, lung cancer
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