Translational aspects of Nuclear Factor - kappa B and its modulation by thalidomide on early and late radiation sequelae in urinary bladder dysfunction

This preclinical study aimed to investigate the role of NF- κB in early and late radiogenic sequelae of urinary bladder dysfunction in mice. Thalidomide was applied either during the early or late response phase to determine potential effects of NF-κB inhibition on functional bladder impairment.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research