Transepidermal Water Loss (TEWL)-decreasing Effect by Administration of Zinc in the Elderly People.

[Transepidermal Water Loss (TEWL)-decreasing Effect by Administration of Zinc in the Elderly People]. Yakugaku Zasshi. 2020;140(2):313-318 Authors: Deguchi M, Jose H, Nishida K, Ooi K Abstract In recent years, it has become clear that zinc deficiency is closely related in several skin disorders. In elderly people, chronic itch and dry skin are common. In addition, the zinc concentrations are known to decrease with age. Therefore, we examined the beneficial effects of oral zinc supplementation on dry skin and itch in elderly people. Patients 65 years of age or older who visited the Jose Clinic (Odai-town, Mie Pref.) with serum zinc concentrations below 80 μg/dL were enrolled in the study (low zinc group). The participants were administered zinc acetate hydrate for 12 weeks from the start of the study, and transepidermal water loss (TEWL) and stratum corneum moisture content measurements, blood collection, and itch evaluation were performed every 4 weeks. Patients in the control group had serum zinc concentrations of ≥80 μg/dL (the normal zinc group). Results showed that TEWL was significantly higher in the low zinc group than in the normal zinc group, indicating that skin barrier function is impaired in the low zinc group. Serum zinc concentrations increased and TEWL decreased significantly over the 12 weeks of treatment. In addition, a negative correlation was observed between serum zinc concentrations and TEWL. Our results indicate that zinc su...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - Category: Drugs & Pharmacology Authors: Tags: Yakugaku Zasshi Source Type: research

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Conclusion: Mite populations with reduced susceptibility to permethrin exist in Austria and necessitate the evaluation of alternative treatment regimens.Key MessagesHuman scabies is a rising major public health issue worldwide and has been designated as a neglected tropical disease by the World Health Organization.Resistance to permethrin, the most widely prescribed first-line therapy for scabies is to date underreported.At present, treatment recommendations remain controversially discussed as official guidelines do not address current development of resistances, and therefore their clinical applicability is limited. P...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
ECZEMA could be treated by using creams, moisturisers or emollients. But you could lower your risk skin condition at home by using this cheap natural oil as a moisturiser. Should you find a new remedy to relieve the itchy and sore signs of eczema?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This article summarizes some clinical shortcuts. Simple procedures such as taking a detailed medical history can provide clues to the underlying cause of chronic pruritus in order to achieve targeted diagnostic workup or to avoid unnecessary testing. If clinical shortcuts are not identified, we recommend a structured medical history, which is also discussed in this article. PMID: 32488462 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
In babies, eczema usually shows up as an itchy, red patch on the cheeks, chin, or scalp and the front of arms and legs. If you see these signs, doctors recommend the “soak and seal” method.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Authors: Ondriska F, Boldiš V, Stanislavová M, Antolová D, Miterpáková M, Hanáček A, Vešperová S, Jančovič I Abstract Dirofilaria repens is the causative agent of human subcutaneous or, less often, ocular dirofilariasis. The work presents a rare case of ocular dirofilariasis manifested by previous subcutaneous migration accompanied by severe headache symptoms. In February 2017, a 58-yr-old man from Trnava region, western Slovakia, noticed red and itchy stripes on his left leg. Inflamed but painless stripes disappeared and showed up again every 5-7 days, mig...
Source: Iranian Journal of Parasitology - Category: Parasitology Tags: Iran J Parasitol Source Type: research
Conditions:   Pediculus Capitis;   Pruritus Intervention:   Other: VAS and 5-D itch pruritus assessment Sponsor:   Indonesia University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Capone K, Kirchner F, Klein SL, Tierney NK Abstract Atopic dermatitis is characterized by dry, itchy, inflamed skin with a dysbiotic microbiome. In this clinical study (NCT03673059), we compared the effects of an eczema cream containing 1% colloidal oat and a standard moisturizer on the skin microbiome and skin barrier function of patients with mild to moderate eczema. Patients were randomly assigned to treatment with 1% colloidal oat eczema cream or a standard, non-fragranced daily moisturizer. Treatment lasted 14 days, followed by a 7-day regression period. Of 61 patients who completed the study, 30 rece...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Conditions:   Pediculus Capitis;   Pruritus Intervention:   Other: VAS and 5-D itch pruritus assessment Sponsor:   Indonesia University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ECZEMA could be treated by using creams, moisturisers or emollients. But you could lower your risk skin condition at home during the coronavirus lockdown by using this sweet treat as a moisturiser. Should you find a new remedy to relieve the itchy and sore signs of eczema?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Abstract Itch and pain are important attention-demanding sensations that allow adaptive responses to potential bodily harm. An attentional bias towards itch and pain stimuli, i.e. preferential attention allocation towards itch- and pain-related information, has been found in healthy, as well as patient groups. However, it remains unclear whether attentional bias for itch and pain differs from a general bias towards negative information. Therefore, this study investigated attentional bias towards itch and pain in 70 itch- and pain-free individuals. In an attention task, itch- and pain-related stimuli, as well as ne...
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
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