Risk factors for Chlamydia trachomatis infection and preterm birth in pregnant Japanese women: Does chlamydial infection cause preterm birth?

Risk factors for Chlamydia trachomatis infection and preterm birth in pregnant Japanese women: Does chlamydial infection cause preterm birth? Jpn J Infect Dis. 2020 Jan 31;: Authors: Cho T, Aoki S, Saigusa Y, Shindo R, Obata S, Kasai M, Enomoto K, Miyagi E Abstract To clarify the risk factors for chlamydial infection and determine whether infection during pregnancy is associated with preterm birth in Japanese women. The subjects were women who underwent Chlamydia trachomatis polymerase chain reaction testing during a singleton pregnancy and delivered after the 22nd week of gestation at a tertiary care center between January 1, 2000 and December 31, 2016. We compared Chlamydia-positive (n=259) and Chlamydia-negative (n=1,974) groups and evaluated the pregnancy outcomes. The Chlamydia-positive group had a higher rate of public assistance coverage, smoking during pregnancy, nulliparity, lack of a partner, presence of other sexually transmitted infections, high-risk social status, and younger age (p
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research

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Current Canadian guidelines for adolescent obstetrical care recommend sexually transmitted infection (STI) screening at entry to care and in the third trimester. Our study assessed the rate of new and recurrent Chlamydia trachomatis (CT) and Neisseria gonorrhea (NG) infections in the third trimester at an adolescent obstetrics clinic. We hypothesized that targeted repeat screening may be appropriate in this adolescent population.
Source: Journal of Pediatric and Adolescent Gynecology - Category: OBGYN Authors: Source Type: research
This study determined if prenatal C. trachomatis infection is associated with preterm birth (PTB) and preeclampsia subtypes. Methods A retrospective cohort study was conducted using 22,772 singleton pregnancies with a prenatal C. trachomatis diagnostic test. Spontaneous and medically indicated PTBs, and term and preterm preeclampsia were outcomes. Modified Poisson regression calculated relative risk (RR) and 95% confidence intervals (CI) with propensity score adjustments stratified by maternal ages
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Original Study Source Type: research
CONCLUSION: Traditional risk factors are associated with increased risk of infection during pregnancy. Prenatal care adequacy and insurance status were associated with the likelihood of being tested. Delays in treatment and tests of reinfection were common. Point-of-care testing and expedited partner therapy should be explored as ways to improve the management of these infections in pregnancy. PMID: 32168225 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
CONCLUSIONS: Based on the results of this systematic review, the POC test based on antigen detection has suboptimal sensitivity but good specificity. Performance of this test translates, on average, to a 52% chance of mistakenly indicating absence of infection and a 2% chance of mistakenly pointing to the presence of this condition. Because of its deleterious consequences for reproductive health, and considering the current availability of safe and effective interventions to treat C trachomatis infection, the POC screening strategy should not be based on a rapid diagnostic test for antigen detection. Research in this topic...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
In 2018, the number of bacterial sexually transmitted infections (STIs) reported in the United States reached an all-time high. This is worrisome for many reasons. Having an STI can raise risks for HIV, infertility, pregnancy complications, and infant death. Fortunately, all of these outcomes can be avoided if people receive appropriate treatment. What are STIs? STIs are illnesses caused by microorganisms passed between people during sex. An STI can affect anyone who is exposed to it. Syphilis, gonorrhea, and chlamydia are the most common bacterial infections. Trichomoniasis, a protozoan infection, is also diagnosed freque...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health HIV Men's Health Relationships Sexual Conditions Women's Health Source Type: blogs
In this study, we evaluated a novel multiplex real-time PCR melting curve assay method for the simultaneous detection of 9 STD pathogens, including Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis, Mycoplasma hominis, Ureaplasma urealyticum, Ureaplasma parvum, and herpes simplex virus.Methods: The analytical performance of the method, including its limit of detection (LOD), specificity, repeatability, and effect on different DNA extraction kits were evaluated. Additionally, we obtained 1,328 clinical specimens from 3 hospitals to detect the 9 STD pathogens using multiplex real-time...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Sexually transmitted disease diagnoses in 2018 broke a record for the fifth consecutive year, according to new data from the U.S. Centers for Disease Control and Prevention (CDC). Chlamydia was the most common STD in 2018, with more than 1.7 million cases reported, followed by more than 580,000 cases of gonorrhea—3% and 5% increases over 2017, respectively. Though less common, syphilis diagnoses also rose, topping 115,000 cases in total, according to the CDC. “These are just infections that were diagnosed and reported,” says Elizabeth Torrone, an epidemiologist at the CDC. Since lots of STDs are asymptoma...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized data visualization Infectious Disease Source Type: news
Abstract Pelvic inflammatory disease (PID) is an infection of the upper genital tract occurring predominantly in sexually active young women. Chlamydia trachomatis and Neisseria gonorrhoeae are common causes; however, other cervical, enteric, bacterial vaginosis-associated, and respiratory pathogens, including Mycobacterium tuberculosis, may be involved. PID can be acute, chronic, or subclinical and is often underdiagnosed. Untreated PID can lead to chronic pelvic pain, infertility, ectopic pregnancy, and intra-abdominal infections. The diagnosis is made primarily on clinical suspicion, and empiric treatment is re...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Deepti Tandon, Kiran Munne, Sanjay Chauhan, Anushree D PatilIndian Journal of Dermatology, Venereology, and Leprology 2019 85(5):441-447 Despite adequate treatment of reproductive tract infection, there is persistence of symptoms in some patients. This raises the possibility of existence of other silent microbes with pathogenic potential. Apart from the common sexually transmitted organisms such as Chlamydia trachomatis and Neisseria gonorrhoeae, there are other silent and emerging pathogens, like genital mycoplasma, which have been associated with cervicitis, pelvic inflammatory disease, infertility, and pregnancy-relate...
Source: Indian Journal of Dermatology, Venereology and Leprology - Category: Dermatology Authors: Source Type: research
Abstract Schistosomiasis afflicts an estimated 10 million pregnant women in Africa annually. With mounting evidence of adverse impacts to reproductive health resulting from urogenital schistosomiasis, including increased transmission of HIV, further research on prenatal disease epidemiology is warranted, with implications for maternal and fetal health. Between October 2016 and March 2017, we conducted a cross-sectional study examining the prevalence of urogenital schistosomiasis and its association with sexually transmitted infections (STIs) other than HIV among pregnant women visiting antenatal clinics in Kisantu...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
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