Dynamic Expression of JC Virus in Urine and its Relationship to Serostatus

ConclusionMS patients displayed a consistent pattern of JCV shedding over days and months in which higher levels of viruria appeared to have driven higher levels of JCV antibody index. The findings provide additional insights into the dynamic expression of JCV and host response; however, studies in larger populations and of longer duration will be needed to determine their significance to the development of progressive multifocal leukoencephalopathy (PML).
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research