Cardiovascular Disorders Mediated by Autonomic Nervous System Dysfunction

Cardiovascular disorders, such as orthostatic hypotension and supine hypertension, are common in patients with neurodegenerative synucleinopathies such as Parkinson disease (PD), and may also occur in other conditions, such as peripheral neuropathies, that result in autonomic nervous system (ANS) dysfunction. Dysfunction and degeneration of the ANS are implicated in the development of orthostatic and postprandial hypotension and impaired thermoregulation. Neurogenic orthostatic hypotension (nOH) results from sympathetic failure and is a common autonomic disorder in PD. Supine hypertension may also occur as a result of both sympathetic and parasympathetic dysfunction in conjunction with nOH in the majority of patients with PD. Management of supine hypertension in the setting of nOH can be counterintuitive and challenging. Additionally, the presence of other noncardiovascular comorbidities, such as diabetes mellitus and peripheral edema, may further contribute to the burden of disease. ANS dysfunction thus presents major healthcare implications and challenges for neurology and cardiovascular practices, necessitating an integrated neurology and cardiology management approach.
Source: Cardiology in Review - Category: Cardiology Tags: Review Articles Source Type: research

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Movement disorders are a group of neurologic conditions characterized phenomenologically by slowness and paucity of movement (hypokinetic disorders) or abnormal excessive involuntary movements (hyperkinesias). The hypokinetic movement disorders are exemplified by Parkinson disease and other parkinsonian disorders. Hyperkinetic movement disorders include tremors, dystonia, tics, chorea, athetosis, ballism, stereotypy, and akathisia. Ataxia, gait disorders, and spasticity are also often included among movement disorders.
Source: Neurologic Clinics - Category: Neurology Authors: Tags: Preface Source Type: research
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Source: Clinics - Category: General Medicine Source Type: research
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Source: Journal of Clinical Gastroenterology - Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research
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Source: Brazilian Oral Research - Category: Dentistry Source Type: research
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Source: Brazilian Oral Research - Category: Dentistry Source Type: research
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Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
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Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
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Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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Source: Life Sciences - Category: Biology Source Type: research
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