An endothelial microRNA-1 –regulated network controls eosinophil trafficking in asthma and chronic rhinosinusitis

Airway eosinophilia is a prominent feature of asthma and chronic rhinosinusitis (CRS), and the endothelium plays a key role in eosinophil trafficking. To date, microRNA-1 (miR-1) is the only microRNA known to be regulated in the lung endothelium in asthma models.

Source: Journal of Allergy and Clinical Immunology - January 31, 2020 Category: Allergy & Immunology Authors: Asawari Korde, Farida Ahangari, Maria Haslip, Xuchen Zhang, Qing Liu, Lauren Cohn, Jose L. Gomez, Geoffrey Chupp, Jordan S. Pober, Anjelica Gonzalez, Shervin S. Takyar Tags: Rhinitis, sinusitis, and ocular allergy Source Type: research