Short-term biological variation and diurnal rhythm of cardiac troponin I (Access hs-TnI) in healthy subjects

ConclusionsTroponin I demonstrates a diurnal rhythm with decreasing values throughout daytime and the peak concentrations in the morning. The circadian variability is statistically significant, but not relevant from a clinical viewpoint. The intra-individual variation (CVI) is lower than that reported in the literature and the index of individuality lower than 0.6 suggests a scarce value of reference interval
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research