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Biomarkers help predict outcome in deadly lung disease

A Yale-led study has identified a gene expression profile that can predict outcomes and lead to better treatment for one of the most lethal lung diseases, idiopathic pulmonary fibrosis (IPF). The study appears in Science Translational Medicine. IPF causes progressive scarring of the lungs, leading to cough, shortness of breath, and potentially death. In most cases, the cause cannot be identified, and there is no cure other than a lung transplant. While some patients experience a progressive course that leads to death within one to two years, others experience a relative stable disease...
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

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Conclusion: The nonspecific chronic symptoms were high among auto-rickshaw drivers as compared to the general population noted from a multicentric study done in India. We recommend that auto-rickshaw drivers should use personal protective equipment and would require regular screening and treatment for respiratory impairment.
Source: Indian Journal of Occupational and Environmental Medicine - Category: Occupational Health Authors: Source Type: research
Conclusions These findings demonstrated the inhibitory effects of AQs, derived from C. occidentalis, on OVA-induced allergic asthma in mice. The results suggest a promising ethnopharmacological use for AQs in patients with asthma. Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Bronchial thermoplasty (BT) is a bronchoscopic treatment for patients with severe asthma who remain symptomatic despite optimal medical therapy. In this “expert best practice” paper, the background and practical aspects of BT are highlighted. Randomized, controlled clinical trials have shown BT to be safe and effective in reducing severe exacerbations, improving quality of life, and decreasing emergency department visits. Five-year follow-up stu dies have provided evidence of the functional stability of BT-treated patients with persistence of a clinical benefit. The Global Initiative for Asthma (GINA) guideline...
Source: Respiration - Category: Respiratory Medicine Source Type: research
CONCLUSIONS: SHSe reduction efforts are critically needed for asthmatic adolescents, and EDs/UCs are promising venues. PMID: 29641269 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Conclusion The asthma group reacted in a predictable way with impaired lung function from osmotic provocations, whereas the patients with CIC demonstrated peripheral airway changes from hypertonic saline, also known to be a noxious stimulus. The IOS method uncovers differences between patients with CIC and control participants that contribute to our ability to provide a correct diagnosis.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research
The objective of this study was to describe the nature and frequency of respiratory symptoms suggestive of bronchospasm developing within 24hours after a MCT. The study was offered to adult patients who underwent MCT seen consecutively between June and October 2015. Following the test, a questionnaire adapted from the GINA asthma control questionnaire bearing on diurnal and nocturnal symptoms (cough, dyspnoea, wheeze and tightness), was delivered to the patient and the replies collected by telephone 24hours later. Of the 101 patients included (initial FEV1 2.82±0.79L), 46 (46 %) were MCT+ and 55 (54 %...
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
ASTHMA symptoms can range from mild to more serious, and not everyone will experience all the signs. It is a common lung condition that can impact hugely on a person ’s life. But there is treatment available to offer quick relief an prevent symptoms occurring.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSION: Spirometry should not be used to screen the military force for the presence of respiratory disorders. In those individuals with a history of asthma, in-depth testing should be performed to fully evaluate any non-specific findings identified during spirometry. PMID: 29590412 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
I was reading ECGs on the computer system when this one came up:What do you think?There is apparent ST elevation in III, with reciprocal ST depression in aVL.  At first glance, it looks like an inferior STEMI.It also has a wavy pattern reminiscent ofhypokalemia.  See these cases:Prehospital Ventricular Fibrillation in a Young Woman. What is the Diagnosis?But it looks very bizarre.  And I knew why. I looked to see what the patients symptoms were, and she was a 30-something woman with symptoms listed as " chest burning. "Then I saw that..... It was I who had seen and discharged this patient!&nbs...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
They fought off some stiff competition, and now we have the final two competitors in MD+DI's 2018 Medtech Startup Showdown. It's down to a battle of digital health dynamos Strados Labs vs. Spry Health, and once again, we're asking you to help us decide which upstart medtech company has what it takes to make it in the real world. You know the drill by now: We'll give readers a week to vote, and the company that gets the most votes is the winner. We'll feature the champ in an upcoming profile on MD+DI (see complete rules here). strados_vs_spry.png Company name Strados Labs S...
Source: MDDI - Category: Medical Devices Tags: Business Source Type: news
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