Bilateral L2 Dorsal Root Ganglion-Stimulation Suppresses Lower Limb Spasticity Following Chronic Motor Complete Spinal Cord Injury: A Case Report

We present the case of a 48-year old male patient with chronic motor complete SCI, who benefited from a 5-day period of bilateral L2-level DRG-stimulation by experiencing suppression of transfer-evoked spasticity problems and of chronic lower back pain. To the best of our knowledge, this is the first case describing the successful application of DRG-stimulation for spasticity depression in patients with chronic SCI.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research

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Contributors : Alexander B Niculescu ; Helen Le-NiculescuSeries Type : Expression profiling by arrayOrganism : Homo sapiensShort-memory dysfunction is a key early feature of Alzheimer Disease. Psychiatric patients may be at higher risk for memory dysfunction and subsequent Alzheimer due to the negative effects of stress and depression on the brain. We carried out longitudinal within-subject studies in male and female psychiatric patients to identify blood gene expression biomarkers that track short term memory as measured by the retention measure in the Hopkins Verbal Learning Test. These biomarkers were prioritized with a...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
The field of abdominal organ transplantation is multifaceted, with the clinician balancing recipient comorbidities, risks of the surgical procedure, and the pathophysiology of immunosuppression to ensure optimal outcomes. An underappreciated element throughout this process is acute pain management related to the surgical procedure. As the opioid epidemic continues to grow with increasing numbers of transplant candidates on opioids as well the increase in the development of enhanced recovery after surgery protocols, there is a need for greater focus on optimal postoperative pain control to minimize opioid use and improve ou...
Source: Transplantation - Category: Transplant Surgery Tags: Reviews Source Type: research
Conclusion: The current review identified strong, high-quality evidence to recommend hip muscle strengthening in the conservative management of persons with knee OA. Further research is needed to establish the underlying mechanisms for the clinical benefits.
Source: Journal of Geriatric Physical Therapy - Category: Physiotherapy Tags: Systematic Reviews Source Type: research
Publication date: Available online 31 March 2020Source: Life SciencesAuthor(s): Mohsen Enayati, Belal Mosaferi, Judith R. Homberg, Danielle Mendes Diniz, Ali-Akbar Salari
Source: Life Sciences - Category: Biology Source Type: research
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Adequate pain control is essential following lung transplantation to reduce patient stress and minimize perioperative complications. Enhanced recovery after surgery (ERAS) protocols have demonstrated improvements in patient experience and reduced length of stay. However, the implementation of these protocols has not yet extended to the lung transplant population.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (209) Source Type: research
Cognitive impairment and mood deviation often occurs in patients with heart failure. Frailty and sarcopenia have been widely studied in patients with heart disease, but cognitive frailty has been little explored. High complexity of patients referred for heart transplantation connected with socioeconomic characteristics in a developing country underlines the importance to investigate cognitive and mood conditions in this population. The aim of the study is to evaluate the prevalence of cognitive impairment and depression symptoms in patients with heart failure in waiting list for heart transplantation (HTx).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (571) Source Type: research
Burnout is common in all types of physicians, but little is known about burnout in lung transplant physicians. The purpose of this study was to explore burnout and its relationship to job factors and depression in lung transplant physicians.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (389) Source Type: research
Postoperative pain for bilateral lung transplant patients is often poorly controlled and may negatively impact recovery. Intercostal cryoanalgesia (IC-CRYO) may provide an additional modality to pain control. We hypothesize that IC-CRYO may enhance recovery compared to traditional opiate based analgesia (OBA) and thoracic paravertebral catheter (TPVC) analgesia.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (458) Source Type: research
Prior studies suggest an association between elevated depressive symptoms following lung transplant (LT) and mortality. We sought to test this association using a longitudinal cohort with 3-years of follow up, and to determine the long-term impact of LT on depressive symptoms.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (282) Source Type: research
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