Quanterix Advances Blood-Based Sports-Related TBI Test with New Study

Quanterix has reached another step in its goal to advance a blood-based test to detect concussions in athletes. The Billerica, MA-based company said researchers have successfully applied the Single Molecule Array (Simoa) technology to generate data on the value of blood biomarkers as research tools to study pathophysiological mechanisms of concussion and as potential clinical tools and objective indicators for sports-related concussions (SRCs) and mild traumatic brain injuries (mTBIs). Results have been published in JAMA Network Open, demonstrate the promise of blood biomarkers to serve as clinical tools for objectively identifying and monitoring head injury, marking a notable advance in the pursuit of a concussion diagnostic test. “What has gone on in this study is, we’re using our sensitivity of Simoa to look at mild traumatic brain injuries,” Kevin Hrusovsky, Chairman and CEO, Quanterix, told MD+DI. “Those two markers that were used in this study -were approved by FDA [about two years ago] to rule out the need to use a CT Scan in the event of a TBI and the company that [behind] that was Banyan Diagnostics.” Results of the study demonstrate a strong correlation between concussions and elevated GFAP, UCH-L1 and tau levels in the blood. The company said this supports prevailing theories that a clinically viable concussion test will necessitate a panel of markers rather than relying on a ...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news

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Phys. Chem. Chem. Phys., 2020, Advance Article DOI: 10.1039/C9CP06925A, PaperSumit Kumar Das, Tara Shankar Bhattacharya, Joydeep Chowdhury Wavelength-scanned SERS spectra of 4-mercaptopyridine molecule adsorbed on gold nanoparticles immobilised in a Langmuir Reverse Schaefer film of 5CB molecules. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
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CrystEngComm, 2020, Advance Article DOI: 10.1039/D0CE00086H, PaperHualan Xu, Ran Liu, Yongmei Zhu, Jinjiang Li, Changfeng Wan, Hang Zhang, Chuying Ouyang, Shengliang Zhong Scandium-based coordination polymer octahedrons with concaved surfaces have been fabricated. The formation mechanism was also investigated. Sc2O3 octahedrons were obtained after simple calcination in a N2 atmosphere. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
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