Burkitt Lymphoma presenting as cranial multineuritis secondary to Primary Neurolymphomatosis: a diagnostic challenge

Neurolymphomatosis (NL) is a devastating complication of non-Hodgkin Lymphoma (NHL) with significant morbidity. It was first described by Baehring et al in 2003 as the direct infiltration of the cranial and peripheral nervous systems by lymphoma cells (1). It is a rare clinical entity, affecting approximately 0.2% of all NHL patients (2). Most cases are due to B-cell NHL (3). Although typically a hallmark of disease progression, it can also be the presenting symptom of a new diagnosis. When this occurs, it is referred to as “Primary NL” (1).

Source: Clinical Lymphoma, Myeloma and Leukemia - February 3, 2020 Category: Hematology Authors: Lindsey Fitzgerald, Deborah M. Stephens Tags: Case Report Source Type: research