Elevated levels of soluble Endothelial protein C receptor in rheumatoid arthritis and block the therapeutic effect of protein C in collagen-induced arthritis.

CONCLUSION: Soluble EPCR is associated with RA disease progression and induces disease remission in CIA mice by inhibiting Th17 differentiation.
PMID: 32007797 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - January 29, 2020 Category: Allergy & Immunology Authors: Bai L, Liu W, Guo P, Bai J, Liu Y, Hua Y, Pang C, Zhang W, Yin F, Wang Y Tags: Int Immunopharmacol Source Type: research