R230C but not − 565C/T variant of the ABCA1 gene is associated with type 2 diabetes in Mexicans through an effect on lowering HDL-cholesterol levels

ConclusionsTheABCA1 rs9282541 (R230C) allele is associated with T2D in Mexicans through its effect on lowering HDL-c levels. This is the first report demonstrating that HDL-c levels act as an intermediate factor between anABCA1 variant and T2D.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research