Analyzing the cost-effectiveness of Lyme disease risk reduction approaches

AbstractLyme disease (LD) is endemic in many regions of the Northeastern United States. Given the elusive nature of the disease, a systematic approach to identify efficient interventions would be useful for policymakers in addressing LD. We used Markov modeling to investigate the efficiency of interventions. These interventions range from awareness-based to behavioral-based strategies. Targeting animal reservoirs of LD using fungal spray or bait boxes did not prove to be an effective intervention. Results of awareness-based interventions, including distribution of signage, fliers, and presentations, implementable in different geographical scales, suggest that policymakers should focus on these interventions, as they are both cost-effective and have the highest impact on lowering LD risk. Populations may lose focus of LD warnings over time, thus quick succession of these interventions is vital. Our modeling results identify the awareness-based intervention as the most cost-effective strategy to lower the number of LD cases. These results can aid in the establishment of effective LD risk reduction policy at various scales of implementation.
Source: Journal of Public Health Policy - Category: Health Management Source Type: research

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Lyme disease (LD) is an increasing public health threat in temperate zones of the northern hemisphere, yet relatively few methods exist for reducing LD risk in endemic areas. Disrupting the LD transmission cyc...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
Abstract Ixodes scapularis is currently known to transmit 7 pathogens responsible for Lyme disease, anaplasmosis, babesiosis, tick-borne relapsing fever, ehrlichiosis, and Powassan encephalitis. Ixodes scapularis can also be colonized by endosymbiotic bacteria including those in the genus of Rickettsia. We screened 459 I. scapularis ticks submitted to the Connecticut Agricultural Experiment Station Tick Testing Laboratory with the objectives to (1) examine differences in infection prevalence of Borrelia burgdorferi, Anaplasma phagocytophilum, Babesia microti, and Borrelia miyamotoi, (2) evaluate whether prevalence...
Source: The Journal of Parasitology - Category: Parasitology Authors: Tags: J Parasitol Source Type: research
Publication date: Available online 31 December 2019Source: Methods in MicrobiologyAuthor(s): Charles S. PaviaAbstractLyme disease and the relapsing fever borrelioses are caused by spirochetal bacteria belonging to the genus Borrelia. They have a partially restricted worldwide distribution depending upon their species. They are transmitted to people following exposure to the following arthropod vectors: ticks (for Lyme disease and endemic relapsing fever) and lice (for epidemic relapsing fever). Soon after a cutaneous infection becomes established, these spirochetes disseminate via the haematogenous route and are capable of...
Source: Methods in Microbiology - Category: Microbiology Source Type: research
NEW YORK (Reuters Health)—In Lyme disease-endemic areas, a C6 peptide enzyme immunoassay (EIA) test may help guide initial management of children with acute arthritis, an observational study suggests.1 “Children with Lyme disease frequently present to the emergency department with an inflamed joint,” Lise Nigrovic, MD, MPH, of Boston Children’s Hospital tells Reuters Health by email.... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions assay C6 peptide enzyme immunoassay (EIA) Lyme arthritis Lyme Disease Source Type: research
In Lyme disease-endemic areas, a C6 peptide enzyme immunoassay (EIA) test may help guide initial management of children with acute arthritis, an observational study suggests.Reuters Health Information
Source: Medscape Orthopaedics Headlines - Category: Orthopaedics Tags: Pediatrics News Source Type: news
Conclusions: A significant increase (P = .02) in Lyme arthritis cases was observed at Oishei Children's Hospital of Buffalo. Lyme arthritis may clinically present similarly to other forms of arthritis, such as oligoarticular juvenile idiopathic arthritis, so health care providers should be aware of distinguishing clinical features, which include rapid onset of swelling and patient age. Because the geographic area of endemic Lyme disease is expanding, all health care providers need to be aware of Lyme arthritis as a possible diagnosis. PMID: 31819695 [PubMed]
Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research
ConclusionThis study of the clinical spectrum of LD in Canadian children underlines the need for preventive measures to protect children in Canada from emerging LD, and the need for health care provider awareness.
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
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Source: Central European Journal of Public Health - Category: International Medicine & Public Health Tags: Cent Eur J Public Health Source Type: research
This article provides an update on changes in case definitions that have been made since the case definitions were last published in 2009, and describes updates that have been made to the interactive website since 2013. Changes were made to the case definitions of five diseases. For hepatitis C, the new case definition now distinguishes between acute and chronic infection. For cyclosporiasis, the probable case definition requires an epidemiologic link, with the clarification that this would likely be due to exposure to a common food source. For rabies, the probable case definition now refers to detection of rabies-neutrali...
Source: Can Commun Dis Rep - Category: Infectious Diseases Authors: Tags: Can Commun Dis Rep Source Type: research
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