Army-developed Zika vaccine induces potent Zika and dengue cross-neutralizing antibodies

(Walter Reed Army Institute of Research) A new study led by WRAIR scientists has shown for the first time that a single dose of an experimental Zika vaccine in a dengue-experienced individual can boost pre-existing flavivirus immunity and elicit protective cross-neutralizing antibody responses against both Zika and dengue viruses. Findings were published today in Nature Medicine. Three Phase 1 human clinical trials have shown ZPIV to be safe and well-tolerated in healthy adults and that it induced a robust immune response.

https://www.eurekalert.org/pub_releases/2020-02/wrai-azv013120.php

Source: EurekAlert! - Infectious and Emerging Diseases - February 3, 2020 Category: Infectious Diseases Source Type: news