Physiologically Based Pharmacokinetic Modeling to Understand the Absorption of Risperidone Orodispersible Film

ConclusionThe main absorption route for risperidone ODF was the gastrointestine. The absorption percentage via oral mucosa was almost negligible due to the physicochemical properties of risperidone although ODF dissolved completely in the oral cavity of Beagle dogs within 2 min.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research