Risk and protective factors for chronic pain following inguinal hernia repair: a retrospective study

ConclusionsThese results indicated that bilateral inguinal hernia repair, preoperative pain, preoperative anxiety, and acute pain at 1  week after the surgery were the independent risk factors for CPSP while low-dose ketamine was the protective factor. These findings may assist with primary prevention by allowing clinicians to screen for individuals with the risk of CPSP.
Source: Journal of Anesthesia - Category: Anesthesiology Source Type: research

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Publication date: 4–10 April 2020Source: The Lancet, Volume 395, Issue 10230Author(s): The Lancet
Source: The Lancet - Category: General Medicine Source Type: research
Conclusion: Results of this study could be used to facilitate radial force control and longitudinal flexibility enhancement in the design of aortic stent-grafts. PMID: 32233714 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
Authors: Mason TM, Tofthagen CS, Buck HG Abstract Complicated grief (CG) poses significant physical, psychological, and economic risks to bereaved family caregivers. An integrative review of the literature published 2009-2018 on CG associated with caregiving was performed using PubMed, PsychINFO, and Web of Science. The search returned 1428 articles, of which 32 were included in the review. Sixteen studies described risk and protective factors and 16 described interventions for CG. Caregiver-related risk factors included fewer years of education, depression, anxiety, poor physical health, and maladaptive dependency...
Source: Journal of Social Work in End-of-Life and Palliative Care - Category: Palliative Care Tags: J Soc Work End Life Palliat Care Source Type: research
Authors: Singh S, Melnik R Abstract Percutaneous thermal ablation has proven to be an effective modality for treating both benign and malignant tumours in various tissues. Among these modalities, radiofrequency ablation (RFA) is the most promising and widely adopted approach that has been extensively studied in the past decades. Microwave ablation (MWA) is a newly emerging modality that is gaining rapid momentum due to its capability of inducing rapid heating and attaining larger ablation volumes, and its lesser susceptibility to the heat sink effects as compared to RFA. Although the goal of both these therapies is...
Source: Electromagnetic Biology and Medicine - Category: Physics Tags: Electromagn Biol Med Source Type: research
The outbreak of coronavirus disease 2019 (COVID-19) may be stressful – it can be difficult to cope with fear and anxiety, changing daily routines, and a general sense of uncertainty. Taking steps to care for your mental health can help you manage stress.
Source: National Institute of Mental Health - Category: Psychiatry Authors: Source Type: news
CONCLUSION: New care models need to be developed to integrate mental health care into the current perioperative care practice. PMID: 32234274 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
Authors: Zhou X, Lv X, Zhang L, Yan J, Hu R, Sun Y, Xi S, Jiang H Abstract Ketamine is a widely used general anesthetic and has been reported to demonstrate neurotoxicity and neuroprotection. Investigation into the regulatory mechanism of ketamine on influencing neural development is of importance for a better and safer way of relieving pain. Reverse transcription‑quantitative polymerase chain reaction and western blotting were used to detect the critical neural associated gene expression, and flow cytometry to detect the neural differentiation effect. Hence, in the present study the underlying mechanism of ketam...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
In this study, we focused on the change in DDAH1 in response to moderate exercise and the underlying mechanism of exercise-induced cardiac angiogenesis. Eight-week-old male DDAH1 global knockout (KO) mice and DDAH1flox/flox mice (wild-type) were randomly divided into sedentary groups (control) and swimming groups (exercise). After eight weeks of swimming at five days per week, all the mice were anesthetized and sacrificed. Histological examination and Western blot analysis were performed. There were low levels of myocardial capillaries in DDAH1 KO mice under control and exercise conditions. Notably, exercise elevated DDAH1...
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
This study evaluates the relationship of PA to outcomes after open ventral hernia repair (OVHR).MethodsA prospective institutional database was queried for patients undergoing OVHR. Demographics, operative characteristics, and outcomes were evaluated by the reported PA and the administration of beta-lactam prophylaxis (BLP).ResultsAllergy histories were reviewed in 1178 patients. PA was reported in 21.6% of patients, with 55.5% reporting rash or hives, 15.0% airway compromise or anaphylaxis, and 29.5% no specific reaction. BLP was administered to 76.3% of patients, including 22.1% of PA patients and 89.9% of patients witho...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
This study examines the interaction of multiple comorbidities, including anxiety, depression, chronic pain, and hernia characteristics with outcomes after OVHR.MethodsPatients with anxiety were identified in an existing, prospectively collected, data set of OVHR with preoperative work-up including CT scans (2007 –2018). A patient with a diagnosis or prescription for anxiolytics, anti-depressants, or narcotics was considered to have anxiety, depression, or chronic pain, respectively. Hernia characteristics were analyzed using 3D volumetric software. Univariate and multivariate analyses were performed to as sess for th...
Source: Hernia - Category: Sports Medicine Source Type: research
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