Economic burden and cost-utility analysis of three renal replacement therapies in ESRD patients from Yunnan Province, China

AbstractPurposeTo compare the economic burden and cost-utility analysis of the renal replacement therapies, including hemodialysis (HD), peritoneal dialysis (PD), and allograft kidney transplantation (KT) among end-stage renal disease (ESRD) patients from Yunnan Province, China.MethodsMultistage stratified random sampling method was used to select presentative sample of 298 patients from four hospitals in Yunnan Province. The two-step model was applied to calculate a direct economic burden; the human capital approach was used to analyze the indirect economic burden. SF-36 scale was applied to assess the quality of life, while the improving score of quality of life was used to evaluate the cost-utility score.ResultsA total of 298 patients were analyzed, including 108 HD patients, 91 PD patients and 99 KT patients. The mean unit economic expenses of HD, PD, and KT were $11,783.6  ± 402.63, $11,059.8 ± 709.51, and $21,151.1 ± 11,419.57, respectively. Based on the cost-utility analysis, the cost of improving one unit of quality of life in KT, PD, and HD was $599.86, $1373.89 and $2021.20, respectively; a significant difference was observed between the KT group and the HD or PD group (P 
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research

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CONCLUSION MIC administration was safe and could be a future tool for the targeted induction of tolerogenic Bregs.TRIAL REGISTRATION EudraCT number: 2014-002086-30; identifier: NCT02560220FUNDING Federal Ministry for Economic Affairs and Technology, Berlin, Germany, and TolerogenixX GmbH, Heidelberg, Germany.
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Ziting Wang, Pradeep Durai, Ho Yee TiongIndian Journal of Urology 2020 36(2):89-94There is an increasing gulf between demand and supply for kidneys in end-stage renal failure patients worldwide, especially Asia. Renal transplantation is often the treatment of choice for long-suffering patients who have to undergo dialysis on a regular basis. The utilization of expanded criteria donors (ECDs) to address the donor pool shortage has been proven to be a legitimate solution. Metzger first described the classification of standard criteria donor and ECD in 2002. Since then, the criterion has undergone various modifications, with ...
Source: Indian Journal of Urology - Category: Urology & Nephrology Authors: Source Type: research
Ganesh B Sonawane, Krishna H Moorthy, Biju S PillaiIndian Journal of Urology 2020 36(2):142-143The left renal vein (LRV) passing behind the abdominal aorta is termed as a retroaortic LRV (RLRV) and it is a relatively uncommon condition. Since the left kidney is preferred in the setting of live donor kidney transplantation, urologists must be familiar with the anomalies of the LRV. There are four variants of RLRV mentioned in the literature. However, we came across two newer variants of RLRV in two donors for renal transplantation. Both donors underwent successful left donor nephrectomy.
Source: Indian Journal of Urology - Category: Urology & Nephrology Authors: Source Type: research
ConclusionThe incidence of post-transplant UTI is similar in both developed and developing countries.E.coli is the most common pathogen in most of studies. Cadaveric donor and post-dialysis transplantation are defined as independent risk factors for post-transplant UTI. Further studies are still required to identify risk factors after kidney transplantation and UTI ’s importance for graft function and patient outcome.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Condition:   Chronic Allograft Injury Interventions:   Drug: UCB7858;   Drug: Placebo Sponsor:   UCB Biopharma SRL Active, not recruiting
Source: - Category: Research Source Type: clinical trials
Three otherwise healthy patients go to the emergency department with severe acute respiratory failure. Only one ventilator, required to sustain life until the worst of the coronavirus infection has passed, is available. Who gets the vent? That’s what “A Framework for Rationing Ventilators and Critical Care Beds During the COVID-19 Pandemic,” a Viewpoint just published in the Journal of the American Medical Association (JAMA), addresses. Douglas White, MD, MAS, Endowed Chair for Ethics in Critical Care Medicine at the University of Pittsburgh School of Medicine ...
Source: - Category: Medical Ethics Authors: Tags: Health Care Author: Lewis syndicated Source Type: blogs
Deceased-donor transplantations, deemed essential surgeries, are moving forward, but surgeons are having to use best judgment to determine whether the kidney's donor was infected with COVID-19.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Nephrology News Source Type: news
MONDAY, April 6, 2020 -- Transplanting hepatitis C virus (HCV)-infected kidneys into uninfected recipients and then treating patients with antiviral therapy leads to a higher quality of life and is less costly than waiting for transplantation with...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
Drug firm Lupin on Monday said it has launched generic Mycophenolic acid delayed-release tablets, which is used to prevent organ rejection in patients receiving kidney transplants in the US market.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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