Targeting CSPG4 for isolation of melanoma cell-derived exosomes from body fluids.

Targeting CSPG4 for isolation of melanoma cell-derived exosomes from body fluids. HNO. 2020 Jan 31;: Authors: Ferrone S, Whiteside TL Abstract This manuscript describes the functional properties of the exosomes released from melanoma cells. It details the characteristics of the tumor antigen chondroitin sulfate proteoglycan 4 (CSPG4), which is used as a marker to separate exosomes released by melanoma cells from exosomes released by nonmalignant cells. The results are discussed in view of the potential role of melanoma cell-derived exosomes in the escape of malignant cells from the host's immune system. PMID: 32006045 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research

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