Anxiety Disorders in the DSM-5: Changes, Controversies, and Future Directions.

Anxiety Disorders in the DSM-5: Changes, Controversies, and Future Directions. Adv Exp Med Biol. 2020;1191:187-196 Authors: Park SC, Kim YK Abstract Under the partial influences of paradigm shift form category to dimension, the Diagnostic and Statistical Manual of Mental Disorder (DSM) was revised to the fifth edition (DSM-5); however, due to the lack of consistent biological makers and processes and the restricted availability of dimensional meta-structure, the revisions for the DSM-5 were based on a combination of categorical and dimensional approaches. Anxiety disorders were more clearly and consistently defined in the DSM-5 with the removal of obsessive compulsive, acute stress, and post-traumatic stress disorders. Differences between the childhood and adulthood categories of anxiety disorders were decreased, and overall, the symmetrical classification of anxiety subtypes was increased, since separation anxiety disorder and selective mutism were considered anxiety disorders, not neurodevelopmental disorders. Additionally, based on growing evidence, agoraphobia is distinct from panic disorder. Next, considering cultural syndromes including taijin kyofusho, khyal cap, trung gio attacks, and ataque de nervios, cultural influences are considered a significant factor for definitions and presentations of anxiety disorders. Controversies in the DSM-5 criteria for anxiety disorders are lowering the diagnostic thresholds of anxiety disorders and limiting the d...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research

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miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4. Mol Med Rep. 2020 May 18;: Authors: Fan Y, Wang K Abstract Colon cancer is one of the most frequent malignant tumors, and microRNA (miR)‑205 is involved in the tumor progression. The present study aimed to explore the effects of miR‑205 on human colon cancer and its targeting mechanism. The levels of miR‑205 and mouse double minute 4 (MDM4) were determined via reverse transcription‑quantitative (RT‑q)PCR and western blot analysis. A luciferase activity assay was performed t...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Conclusions: 60% of patients with MDD and/or AAD had at least one additional NCCD, which significantly increased the economic and humanistic burden. These findings are important for payers and clinicians in making treatment decisions. These results underscore the need for development of multi-pronged interventions which aim to improve quality of life and reduce activity limitations among patients with mental health disorders and NCCDs. PMID: 32468879 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
CONCLUSIONS: Results shed more light toward the possible use of VR for distant self-administered evaluation of the frail status. PMID: 32468314 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Giannoulis K, Giannouli V Abstract The goal of this study is to examine subjective quality of life-life satisfaction, religiousness, and spiritual experience in healthy younger and older adults, as well as in older patients suffering from severe cardiovascular disease, while examining the role of marital status, employment and socioeconomic status, existence of social network, urbanicity, education, depression, and personal opinion about the country's current socioeconomic situation. Results revealed that there are no age differences and that the role of demographic variables as predictors of religiousness...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Persakis E, Kostagiolas P Abstract Cancer is considered as one of the main challenges of modern healthcare systems. Cancer patients are obliged to cope with the uncertainty of disease progression. Their anxiety regarding said uncertainty is intensified because they need to constantly make decisions concerning the management of their disease. Information and communication are considered important in cancer management. As a result, the research associated with the impact of healthcare information-seeking behavior on numerous cancer management aspects has intensified and grown in astonishing rates. This work ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
CONCLUSION: T2DM patients have cognitive deficits on several domains compared to healthy participants. Domain specific neuropsychological deficits in middle aged T2DM patients have a significant impact on HRQOL. PMID: 32468306 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Intas G, Rokana V, Stergiannis P, Chalari E, Anagnostopoulos F Abstract BACKGROUND: Chronic illnesses with high level of disability can affect not only the patients but also the main caregiver who supports them. The aim of this study was to investigate the burden and sleep disorders of family caregivers of hemodialysis patients. METHODS: This is a cross-sectional study. The sample of the study consisted of 310 family caregivers of hemodialysis patients. The tools used were the Pittsburgh Sleep Quality Index (PSQI) for sleep disorders assessment, the Zarit Burden Interview, and the Center for Epidemiolo...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
DISCUSSION: Sleep deprivation etiologies are multifactorial and have several effects on ICU patients. Sleep protocol and staff training should be introduced to reduce unnecessary interventions by ICU staff. Tele-ICU monitoring can also be introduced to reduce unnecessary interventions where clinicians can monitor patients remotely and therefore enhance sleep in the ICU. During their stay in the ICU, patients can be instructed to wear earplugs and also have aromatherapy massage to reduce stress and enhance sleep quality. More research on the physical pain and the psychological factors using objective methods should be condu...
Source: Dimensions in Critical Care Nursing - Category: Nursing Tags: Dimens Crit Care Nurs Source Type: research
AbstractFor LGBTQ  + individuals, coming out can be an experience of marked adversity. Indeed, research has shown that the experience can trigger psychological ill-health (e.g. depression and anxiety) as well as posttraumatic stress symptoms (PTSS) such as sleep disturbance, somatic symptoms and cognitive distress. While studies have investigated the pain associated with coming out, much less is known about the potential for this life event to lead to growth. The aim of the current study, therefore, was to explore levels of posttraumatic stressand the presence of posttraumatic growth (PTG) in LGBTQ  + adults ...
Source: Journal of Happiness Studies - Category: Psychiatry & Psychology Source Type: research
A highly effective psychotherapy called cognitive behavioral therapy (CBT) focuses on how our thoughts, beliefs, and attitudes can affect our feelings and behavior. Traditional CBT treatment usually requires weekly 30- to 60-minute sessions over 12 to 20 weeks. A faster option now emerging is intensive CBT (I-CBT), which employs much longer sessions concentrated into a month, week, or weekend — or sometimes a single eight-hour session. CBT helps people learn tools to reframe different types of thinking, such as black-and-white thinking (I can’t do anything right) and emotional reasoning (I feel you dislike me, ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health Anxiety and Depression Behavioral Health Mental Health Parenting Source Type: blogs
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