The role of programmed cell death ligand-1/ programmed cell death-1 (PD-L1/PD-1) in HPV-induced cervical cancer and potential for their use in blockade therapy.

CONCLUSION: Recent research developments have led to an entirely new class of drugs using antibodies against the PD-L1/PD-1 thus promoting the body's immune system to fight the cancer. The expression and roles of the PD-L1/ PD-1 axis in the progression of cervical cancer provide great potential for using PD-L1/PD-1 antibodies as a targeted cancer therapy.
PMID: 32003657 [PubMed - as supplied by publisher]

Source: Current Medicinal Chemistry - January 26, 2020 Category: Chemistry Authors: Zhang L, Zhao Y, Tu Q, Xue X, Zhu X, Zhao KN Tags: Curr Med Chem Source Type: research