Protective effect of sodium propionate in A β1-42 -induced neurotoxicity and spinal cord trauma.

In conclusion, our results demonstrated that SP possesses neuroprotective effects, suggesting it could represent a target for therapeutic intervention in neuroinflammatory disorders. PMID: 32004548 [PubMed - as supplied by publisher]
Source: Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Neuropharmacology Source Type: research

Related Links:

Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Kehinde S. Olaniyi, Oluwatobi A. Amusa
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 24 May 2020Source: PhytomedicineAuthor(s): Hai-Qiao Wang, Min Liu, Liang Wang, Fen Lan, Yi-Han Zhang, Jin-Er Xia, Zhen-Dong Xu, Hai Zhang
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
DEMENTIA currently has no cure, but scientists have been looking into ways different types of dementia can be prevented. In a new study, three foods have been shown to have protective benefits against Alzheimer's disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
HDAC1 is involved in a form of DNA repair, but levels decline with age, as well as in Alzheimer's disease. This leads to a greater accumulation of unrepaired oxidative DNA damage in neurons. Researchers here note that increased activation of HDAC1 appears to improve cognitive function via a reduction in this oxidative DNA damage. An HDAC1 activator drug has been tested as a treatment for dementia, but caused serious side-effects. Better compounds or other approaches may be able to obtain similar benefits without the harms. There are several members of the HDAC family of enzymes, and their primary function is to m...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Condition:   Periodontal Diseases Intervention:   Drug: Sodium hypochlorite gel application Sponsor:   University of Messina Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In Sketchy they say Sodium Bicarbonate is used to treat TCA overdose. One of the reasons they say is because it increases serum pH which favors the non-ionized form of the drug. Why is this? I thought increase serum pH> less H+. Then to compensate for this decrease in H+, wouldn't TCA ionize more to replace to lost H+ ions?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Medical Students - MD Source Type: forums
Abstract We used five types of surfactants assisted with sodium salts, including sodium tartrate (ST), sodium chloride (SC), and humic acid sodium (HAS) as auxiliary agents for soil washing to remove diesel from contaminated soil. Decontamination enhancement of diesel polluted soil washing with biosurfactant and H2O2 was examined, which showed higher effectiveness for newly contaminated soil. An increase in temperature and sodium salt addition exhibited a profound enhancement in diesel removal from aged contaminated soils. Compared to ST and SC, HAS exhibited a higher removal efficiency with saponin washing for ag...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
Abstract Three spectrophotometric methods have been developed and compared for the quantification of low concentrations (0.03-63 μM) of aqueous permanganate in neutral pH conditions. Although permanganate is a widely used oxidant in drinking water and wastewater treatment, no widely accepted method of quantification has been reported to date. While one method presented does not require the need for any reagent chemicals (direct spectrophotometric analysis), it yielded a relatively low molar absorption coefficient of 3340 M-1 cm-1 at 525 nm and a level of detection (LOD) and quantification (L...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
Uptake and toxicity of di-(2-ethylhexyl) phthalate in Brassica chinensis L. Chemosphere. 2020 Aug;252:126640 Authors: Yuan L, Cheng J, Wang Y, Liu Y, Wang W, Gao R, Yu X Abstract This work focuses on the bioaccumulation and toxic effects of di-(2-ethylhexyl) phthalate (DEHP) in the leafy vegetable Shanghaiqing (SHQ) (Brassica chinensis L.). The accumulated DEHP amount in the edible part and roots of SHQ increased as the DEHP concentration in the soil increased. DEHP accumulation was higher in the roots than in the edible part of the plant. The root concentration factors and bioaccumulation factor...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
In this study, technologies of different types of hospital wastes and wastewater disinfection have been summarized. Liquid chlorine, sodium hypochlorite, chlorine dioxide, ozone, and ultraviolet irradiation disinfection are commonly used for hospital wastewater disinfection. While incineration, chemical disinfection, and physical disinfection are commonly used for hospital wastes disinfection. In addition, considering the characteristics of various hospital wastes, the classification and selection of corresponding disinfection technologies are discussed. On this basis, this study provides scientific suggestions for managem...
Source: Environmental Pollution - Category: Environmental Health Authors: Tags: Environ Pollut Source Type: research
More News: Alzheimer's | Brain | Drugs & Pharmacology | Neuroblastoma | Neurology | Sodium | Spinal Cord Injury | Study | Translocation