Utility of the platelet function analyser (PFA-100/200) for exclusion or detection of von Willebrand disease: A study 22  years in the making

von Willebrand disease (VWD) is the most common inherited bleeding disorder and may alternatively arise as an acquired condition (AVWS). These represent deficiency and/or defects in von Willebrand factor (VWF). Closure times (CTs) obtained from the platelet function analyser (PFA) are highly sensitive to both VWD/AVWS. The current study has evaluated the utility of the PFA-100/-200 to exclude or detect laboratory identified VWD.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Full Length Article Source Type: research