Video beats brochure to prep smokers for CT screening

A video with information about CT lung cancer screening was more effective...Read more on AuntMinnie.comRelated Reading: CT lung screening websites may be misleading patients Is shared decision-making CT lung screening's Trojan horse? Doctors continue to forgo CT lung screening discussions Can videos convince smokers to get CT lung screening? New decision aids may revamp CT lung cancer screening
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Abstract INTRODUCTION: The prevalence and burden of age-related non-AIDS comorbidities (NACM) is poorly characterized among women living with HIV (WLWH). METHODS: Virologically-suppressed WLWH and HIV-seronegative participants followed in the Women's Interagency HIV Study (WIHS) through ≥2009 (when>80% WLWH used antiretroviral therapy) were included, with outcomes measured through 3/31/2018. Covariates, NACM number and prevalence were summarized at most recent WIHS visit. We used linear regression models to determine NACM burden by HIV serostatus and age. RESULTS: Among 3232 women (2309 WLWH, 923 H...
Source: Clinical Lung Cancer - Category: Cancer & Oncology Authors: Tags: Clin Infect Dis Source Type: research
The objective of this research was to estimate the incidence of malignancies in HIV patients and their surveillance. Age and sex-adjusted incidence was compared to the incidence calculated by the Spanish Cancer Registry network (REDECAN) in 2015. RESULTS: We included 2,773 patients (41,238 patients-year). Two hundred and eleven malignancies were diagnosed in 182 patients. Non-AIDS defining cancers accounted for 78.2% of the malignancies. The global incidence of cancer was 485 cases per 100,000 person-years. Twenty-year mortality rate was 31.2% in patients with cancer and 7.8% in patients without cancer. In men, adjuste...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Abstract The HIV infection remains a serious public health concern in France and around the World. Cancers are frequent among people living with HIV (PLWH) and have become the leading cause of mortality among this population in France. Certain non-AIDS-defining cancers are much more common among PLWH, such as anal carcinoma, Hodgkin lymphoma, hepatocellular carcinoma and lung cancer. The incidence of cancer among PLWH depending on various factors, virological control under combined antiretrovial therapies (cART), exposure prevention to oncogenic virus and toxics are of utmost importance, such as the implementation...
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
CONCLUSION: The rate of PTDI is quite high in patients using TKIs. Effort must be made to increase awareness of this subject. Increasing awareness aids in lowering toxicity rates and providing efficient antitumor therapy. PMID: 31646831 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
This study demonstrates the inhibition activity of kaempferol and myricetin and the structure-function relationship of these two flavonoid and previously isolated flavonoids from Vernonia cinerea and Pluchea indica against both enzymes. 3. Kaempferol could inhibit CYP2A6 with Kic value of 1.77 ± 0.47 µM while inhibit CYP2A13 with Kic value of 0.12 ± 0.01 µM. Myricetin could inhibit CYP2A6 with Kic value of 4.06 ± 0.52 µM while inhibit CYP2A13 with Kic value of 1.88 ± 0.03 µM. 4. Molecular docking indicated that CYP2A...
Source: Xenobiotica - Category: Research Authors: Tags: Xenobiotica Source Type: research
CONCLUSIONS: While clinicians feel that LDCT LCS may benefit some HNC survivors, there are barriers both to implementing LCS SDM for these patients in primary care as currently recommended and to integrating it into cancer clinics. Challenges for SDM across settings include a lack of decision aids tailored to patients with cancer histories. Given recommendations to broaden LCS eligibility criteria, more research may be required before refinement of current guidelines. PMID: 31409114 [PubMed - as supplied by publisher]
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
Conclusion: Treatment with PD-1 inhibitors seems to have an efficacy signal and be well tolerated in PLWHIV, including impact on CD4+ lymphocyte count and HIV load, that should be monitored during treatment course (regarding real-life experience).
Source: AIDS - Category: Infectious Diseases Tags: FAST TRACK Source Type: research
In Reply We thank De Allie and colleagues for their comments on our article. We agree that many primary care physicians (PCPs) lack skills in shared decision making (SDM), particularly SDM using decision aids. This lack should be ameliorated by incorporation of education on decision aids into undergraduate, postgraduate, and continuing medical education. Formal SDM with decision aids is one method to promote patient-centered medicine, as are good listening skills and sufficient time budgeted for clinical encounters to create space for patients to express their values and preferences.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
ConclusionsThe use of intraoperative electromagnetic transthoracic nodule localization prior to thoracoscopic resection of small and/or difficult to palpate lung nodules is safe and effective, potentially eliminating the need for direct nodule palpation. Use of this technique aids in minimally invasive localization and resection of small, deep and/or ground-glass lung nodules.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 20 June 2019Source: Biochimica et Biophysica Acta (BBA) - BioenergeticsAuthor(s): Harry G. Sherman, Carolyn Jovanovic, Alaa Abuawad, Dong-Hyun Kim, Hilary Collins, James E. Dixon, Robert Cavanagh, Robert Markus, Snow Stolnik, Frankie J. RawsonAbstractTrans-plasma membrane electron transfer (tMPET) is a process by which reducing equivalents, either electrons or reductants like ascorbic acid, are exported to the extracellular environment by the cell. TPMET is involved in a number of physiological process and has been hypothesised to play a role in the redox regulation of cancer metabolism. ...
Source: Biochimica et Biophysica Acta (BBA) Bioenergetics - Category: Biochemistry Source Type: research
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