Roles for Exosome in Various Kidney Diseases and Disorders
This article summarizes roles of the exosome as the potential source of biomarkers, pathogenic molecules, and therapeutic biologics that have been extensively investigated in many kidney diseases/disorders, including lupus nephritis (LN), other glomerular diseases, acute kidney injury (AKI), diabetic nephropathy (DN), as well as in the process of renal fibrosis and chronic kidney disease (CKD) progression, in addition to polycystic kidney disease (PKD), kidney transplantation, and renal cell carcinoma (RCC). Moreover, the most recent evidence has shown its emerging role in kidney stone disease (or nephrolithiasis), involving inflammasome activation and inflammatory cascade frequently found in kidney stone pathogenesis.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
More News: Biology | Cancer & Oncology | Carcinoma | Chronic Kidney Disease | Cytology | Diabetes | Drugs & Pharmacology | Endocrinology | Kidney Cancer | Kidney Stones | Kidney Transplant | Kidney Transplantation | Lupus | Nanotechnology | Nephritis | Physiology | Polycystic Kidney Disease | Renal Cell Carcinoma | Transplants | Urology & Nephrology