Safety, Tolerability and Pharmacokinetics of Single Dose Polyethylene Glycolated Exenatide Injection (PB-119) in Healthy Volunteers

ConclusionThe administration of polyethylene glycolated exenatide injection at a single dose of 2 –200 µg is safe and tolerable for healthy volunteers. Once-weekly polyethylene glycolated exenatide injection can be recommended.Clinical Trials RegistrationThe study was registered at clinicaltrials.gov (No. NCT02084251).
Source: European Journal of Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research