Protective Effect of Circular RNA (CircRNA) Ddx17 in Ovalbumin (OVA)-Induced Allergic Rhinitis (AR) Mice.

CONCLUSIONS CircDdx17 appears to have a protective effect on mice in the progression of AR. Specifically, overexpression of circDdx17 inhibited the expression of miR-17-5p and alleviated the condition of AR. Therefore, circDdx17 appears to be a good candidate for use in prevention of AR. However, the detailed mechanism underlying the circDdx17/miR-17-5p regulatory pathway requires further study. PMID: 31999672 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31999672?dopt=Abstract

Source: Medical Science Monitor - January 31, 2020 Category: Research Tags: Med Sci Monit Source Type: research