Mitochondrial oxidative phosphorylation and mitophagy in myocardial ischaemia/reperfusion: effects of chloroquine.

CONCLUSIONS: Ischaemia/reperfusion-induced changes in mitochondrial oxidative phosphorylation function occurred concomitantly with changes in mitophagic flux. Pre-treatment with chloroquine profoundly affected mitochondrial function as well as the pattern of mitophagy during ischaemia/reperfusion. PMID: 31995116 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31995116?dopt=Abstract

Source: Cardiovascular Journal of Africa - December 11, 2019 Category: Cardiology Authors: Dhanabalan K, Huisamen B, Lochner A Tags: Cardiovasc J Afr Source Type: research