Higher doses of loop diuretics limit uptitration of angiotensin-converting enzyme inhibitors in patients with heart failure and reduced ejection fraction

ConclusionsHigher doses of loop diuretics limited uptitration of ACEi in patients with HFrEF and were associated with a higher risk of death and/or HF hospitalization, independent of their lower likelihood of uptitration and higher baseline risk.Graphic abstract This figure was created with images adapted from Servier Medical Art licensed under a Creative Commons Attribution 3.0
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research