Four new quinolizidine alkaloids from the flowers of Sophora viciifolia

Publication date: April 2020Source: Phytochemistry Letters, Volume 36Author(s): Dan-Dan Gao, Zhi-Jun Zhang, Hong-Mei Li, Xuan-Qin Chen, Dan Liu, Rong-Tao LiAbstractFour new quinolizidine alkaloids, including three matrine-type alkaloids, 8α-hydroxysophocarpine (1), 13β-hydroxyoxymatrine (2), 9α-acetoxymatrine (3), and one sparteine-type alkaloid, 14β-hydroxylupanine (4), together with four known ones, were isolated from the flowers of Sophora viciifolia. Their structures were elucidated by extensive spectroscopic methods including 1D-, 2D-NMR, and HR-ESI-MS. All of the isolates were evaluated for their anti-inflammatory and anti-influenza virus activities. Unfortunately, none of them were active towards these assays.Graphical abstract

Source: Phytochemistry Letters - January 30, 2020 Category: Chemistry Source Type: research