Fusion Imaging: A Novel Diagnostic Tool for Nerve-sparing Surgery for Deep Infiltrating Endometriosis

Publication date: February 2020Source: Journal of Minimally Invasive Gynecology, Volume 27, Issue 2Author(s): Marco Scioscia, Bruna A. Virgilio, Arnaldo Scardapane, Giovanni Pontrelli
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research

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Conclusions: Lower back pain is a serious health problem, and this review article will help educate physicians and physiotherapists dealing with LBP in the options of evidence-based treatment. Ultimately, the article introduces and postulates the need to systematize therapeutic procedures in LBP therapy, with a long-term perspective. PMID: 32256908 [PubMed - as supplied by publisher]
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
Conditions:   Endometriosis;   Bowel Endometriosis;   Endometriosis, Rectum;   Endometriosis Colon Intervention:   Behavioral: Expectant management Sponsor:   Ospedale Policlinico San Martino Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 6 April 2020Source: Journal of Minimally Invasive GynecologyAuthor(s): Noah B RINDOS, Isabel R FULCHER, Nicole M DONNELLAN
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
This article will review the current medical therapies in use in the management of endometriosis-related pain and describe potential imaging-related findings expected with these therapies.
Source: Abdominal Imaging - Category: Radiology Source Type: research
Conditions:   Endometriosis;   Covid19 Intervention:   Sponsor:   Kanuni Sultan Suleyman Training and Research Hospital Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractApoptosis-stimulating p53 protein 2 (ASPP2) is an apoptosis inducer that acts via binding with p53 and epithelial polarity molecule PAR3. Lipolysis-stimulated lipoprotein receptor (LSR) is an important molecule at tricellular contacts, and loss of LSR promotes cell migration and invasion via Yes-associated protein (YAP) in human endometrial cancer cells. In the present study, to find how ASPP2 suppression promotes malignancy in human endometrial cancer, we investigated its mechanisms including the relationship with LSR. In endometriosis and endometrial cancers (G1 and G2), ASPP2 was observed as well as PAR3 and LSR...
Source: Histochemistry and Cell Biology - Category: Biomedical Science Source Type: research
Condition:   Endometriosis Interventions:   Drug: 75 mg linzagolix tablet;   Drug: 200 mg linzagolix tablet;   Drug: Placebo tablet to match 75 mg linzagolix tablet;   Drug: Placebo tablet to match 200 mg linzagolix tablet;   Drug: Add-back capsule (E2 1 mg / NETA 0.5 mg);   Drug: Placebo capsule to match Add-ba ck capsule Sponsor:   ObsEva SA Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Endometriosis Interventions:   Drug: 75 mg linzagolix tablet;   Drug: 200 mg linzagolix tablet;   Drug: Placebo tablet to match 75 mg linzagolix tablet;   Drug: Placebo tablet to match 200 mg linzagolix tablet;   Drug: Add-back capsule (E2 1 mg / NETA 0.5 mg);   Drug: Placebo capsule to match Add-ba ck capsule Sponsor:   ObsEva SA Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
(Oregon State University) Scientists have developed a precise, nanotechnology-based treatment to alleviate the pain and fertility problems associated with endometriosis, a common gynecological condition in women of childbearing age.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
This study presents a nanoplatform that concurrently delineates and ablates endometriosis tissues using real‐time near‐infrared (NIR) fluorescence and phototherma l therapy (PTT). The nanoplatform consists of a dye, silicon naphthalocyanine (SiNc), capable of both NIR fluorescence imaging and PTT, and a polymeric nanoparticle as a SiNc carrier to endometriosis tissue following systemic administration. To achieve high contrast during fluorescence imaging of en dometriotic lesions, nanoparticles are constructed to be non‐fluorescent prior to internalization by endometriosis cells. In vitro studies confirm that these na...
Source: Small - Category: Nanotechnology Authors: Tags: Full Paper Source Type: research
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