Pregnancy outcomes amongst multiple sclerosis females with third trimester Natalizumab use.

Conclusions: Complications following natalizumab administration during the second and third trimester of pregnancy occurred in 33% of newborns. However, did not result in mortality or morbidity. Dose alterations during the third trimester, pre-delivery umbilical cord sampling and IVIG administration may reduce hematological effects on newborns. Prospective studies with larger numbers of patients are required to provide further evidence regarding the safety of Natalizumab use in pregnancy.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research