Skin Biomechanics and miRNA Expression Following Chronic UVB Irradiation.
Conclusion: The data suggest that UVB alters miR-34 family expression in skin, in addition to dysregulating collagen structure with subsequent reductions in strength and elasticity. miRNAs may play a pivotal role in regulating extracellular matrix deposition and skin biomechanics following chronic UVB exposure, and thus may be a possible target for therapeutic development. However, additional studies are needed to directly probe the link between UVB exposure, miRNA production, and skin biomechanics.
PMID: 31993250 [PubMed]
Source: Adv Data - Category: Epidemiology Authors: Blackstone BN, Wilgus TA, Roy S, Wulff BC, Powell HM Tags: Adv Wound Care (New Rochelle) Source Type: research