Positive EGFR mutation status is a risk of recurrence in pN0 –1 lung adenocarcinoma when combined with pathological stage and histological subtype: a retrospective multi-center analysis

Lung adenocarcinoma without metastasis to the mediastinal lymph node or distant site is generally an indication for surgical resection. Recurrence can occur even after complete resection, and pathological stage (pStage) and/or histological subtype classification are utilized to predict the risk of recurrence. Epidermal growth factor receptor (EGFR) mutations are one of the most common oncogenic driver mutations of lung adenocarcinoma [1,2] especially in Asia [3,4], and their prognostic implication in lung adenocarcinoma remains controversial.

Source: Lung Cancer - January 28, 2020 Category: Cancer & Oncology Authors: Masaoki Ito, Yoshihiro Miyata, Yasuhiro Tsutani, Hiroyuki Ito, Haruhiko Nakayama, Kentaro Imai, Norihiko Ikeda, Morihito Okada Source Type: research