Repeat expansion and methylation-sensitive triplet-primed polymerase chain reaction for fragile X mental retardation 1 gene screening in institutionalised intellectually disabled individuals.

CONCLUSION: Repeat expansion and methylation-specific TP-PCR is practical, effective and inexpensive for the diagnosis of FXS, especially in high-risk populations of individuals with ID of undetermined aetiology. PMID: 31989181 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31989181?dopt=Abstract

Source: Singapore Medical Journal - January 27, 2020 Category: General Medicine Authors: Sihombing NRB, Cai S, Wong DPW, Guan M, Chong SS, Faradz SMH, Winarni TI Tags: Singapore Med J Source Type: research