Comparison of USPIO-enhanced MRI and Gd-DTPA enhancement during the subacute stage of focal cerebral ischemia in rats.

CONCLUSION: After focal cerebral ischemia, Gd-DTPA-enhanced MRI showed a higher sensitivity in detecting BBB alterations than did USPIO enhancement. USPIO provided complementary information regarding inflammatory cell activity in neuroinflammatory to cerebral ischemia that had not been visualized using conventional Gd-DTPA. The assessment using multiple MR parameters may identify intracellular and extracellular USPIO in vivo. PMID: 24065200 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24065200?dopt=Abstract

Source: Acta Radiologica - September 24, 2013 Category: Radiology Authors: Yang YM, Feng X, Yin LK, Li CC, Jia J, Du ZG Tags: Acta Radiol Source Type: research