Serum cortisol levels in patients with a transient global amnesia.

Serum cortisol levels in patients with a transient global amnesia.
Rev Neurol (Paris). 2020 Jan 24;:
Authors: Schneckenburger R, Hainselin M, Viader F, Eustache F, Quinette P
Abstract
Transient global amnesia (TGA) can be triggered by a high level of blood cortisol. We assessed whether patients had a higher level of cortisol during the TGA than shortly after. We included 52 patients, 21 with blood collected during the TGA episode and 31 shortly thereafter. We compared these two groups after adjustment for time of blood collection. The cortisol level was significantly higher in the per-ictal group (P=0.03) and negatively correlated with the time elapsed from symptom onset (P=0.005). The results are consistent with of the hypothesis of a hyperreactivity of the hypothalamic-pituitary-adrenal axis.
PMID: 31987629 [PubMed - as supplied by publisher]

Source: Revue Neurologique - January 29, 2020 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research