Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3).
CONCLUSIONS: These data provide a better insight into the molecular mechanism beyond the analgesic effect of VAs and propose novel strategies to attenuate TRPM3 dependent nociception.
PMID: 31987857 [PubMed - as supplied by publisher]
Source: Biochemical Pharmacology - Category: Drugs & Pharmacology Authors: Kelemen B, Lisztes E, Vladár A, Hanyicska M, Almássy J, Oláh A, Gábor Szöllősi A, Pénzes Z, Posta J, Voets T, Bíró T, István Tóth B Tags: Biochem Pharmacol Source Type: research
More News: Anesthesia | Anesthesiology | Brain | Drugs & Pharmacology | Neurology | Sevoflurane | Ultane