Comparison of body mass index and metabolic parameters with serum vaspin levels in women with polycystic ovary syndrome

This study showed that there is a positive correlation between serum Visceral Adipose tissue derived Serine Protease Inhibitor (VASPIN) level and polycystic ovary syndrome (PCOS). In previous studies, this relation was attributed to the generalization of higher amount of adipose tissue in patients with PCOS. However, we detected that VASPIN is significantly high in patients with PCOS regardless of BMI. We also showed that metabolic parameters such as fasting insulin, HOMA-IR, triglycerides and LDL-C levels were increased in lean women with PCOS.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research