Surgical disconnection of epilepsy network correlates with improved outcomes

For the 20 –30 % of patients with temporal lobe epilepsy (TLE) refractory to medical therapy, resective brain surgery is an effective option that results in seizure freedom in approximately two-thirds of cases [1]. Surgical disconnection of the epileptogenic tissue is the goal of each type of epilepsy surger y, and in TLE this typically occurs with resection of the hippocampus, amygdala, and/or the anterior temporal lobe [2]. Development of technology that allows for more accurate and precise surgical target mapping or better identification of ideal surgical candidates may lead to a higher rate of seizu re-freedom in patients with TLE undergoing surgery.

Source: Seizure: European Journal of Epilepsy - January 27, 2020 Category: Neurology Authors: Elliot G. Neal, Stephanie Maciver, Mike R. Schoenberg, Fernando L. Vale Source Type: research