Effects of Maternal Stress and Nutrient Restriction during Gestation on Offspring Neuroanatomy in Humans

Publication date: Available online 28 January 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Katja Franke, Bea van den Bergh, Susanne R. de Rooij, Nasim Kroegel, Peter W. Nathanielsz, Florian Rakers, Tessa J. Roseboom, Otto.W. Witte, Matthias SchwabAbstractCognitive and mental health are major determinants of quality of life, allowing integration into society at all ages. Human epidemiological and animal studies indicate that in addition to genetic factors and lifestyle, prenatal environmental influences may program neuropsychiatric disorders in later life. While several human studies have examined the effects of prenatal stress and nutrient restriction on brain function and mental health in later life, potentially mediating effects of prenatal stress and nutrient restriction on offspring neuroanatomy in humans have been studied only in recent years. Based on neuroimaging and anatomical data, we comprehensively review the studies in this emerging field. We relate prenatal environmental influences to neuroanatomical abnormalities in the offspring, measured in utero and throughout life. We also assess the relationship between neuroanatomical abnormalities and cognitive and mental disorders. Timing- and gender-specific effects are considered, if reported. Our systematic review provides evidence for adverse effects of an unfavorable prenatal environment on structural brain development that may contribute to the risk for cognitive, behavioral and mental health probl...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research

Related Links:

Publication date: June 2020Source: Journal of Bone Oncology, Volume 22Author(s): Michala Skovlund Sørensen
Source: Journal of Bone Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 4 April 2020Source: Journal of Geriatric OncologyAuthor(s): Kelly M. Trevino, Amy Stern, Holly G. Prigerson
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 4 April 2020Source: Journal of Geriatric OncologyAuthor(s): Isacco Desideri, Carlotta Becherini, Luca Visani, Giulia Stocchi, Erika Scoccimarro, Matteo Mariotti, Viola Salvestrini, Silvia Scoccianti, Daniela Greto, Pierluigi Bonomo, Guido Pecchioli, Lorenzo Bordi, Alessandro Della Puppa, Giulio Francolini, Icro Meattini, Lorenzo Livi
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 4 April 2020Source: Journal of Geriatric OncologyAuthor(s): Joshua B. Cadwell, Anoushka M. Afonso, Armin Shahrokni
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 4 April 2020Source: Journal of Geriatric OncologyAuthor(s): Claire A. Surr, Rachael Kelley, Alys W. Griffiths, Laura Ashley, Fiona Cowdell, Ann Henry, Michelle Collinson, Ellen Mason, Amanda J. Farrin
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 3 April 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Brajesh Kaushal, Sandeep Chauhan, Rohan Magoon, Nitish Naik, Ambuj Roy
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 3 April 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Frederic J. Baud, Vincent Jullien, Philippe-Henri Secrétan, Pascal Houzé, Lionel Lamhaut
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 3 April 2020Source: Anaesthesia &Intensive Care MedicineAuthor(s): Viyayanand Nadella
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 12 March 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Karsten Weller, Tamara Donoso, Markus Magerl, Emel Aygören-Pürsün, Petra Staubach, Inmaculada Martinez-Saguer, Tomasz Hawro, Sabine Altrichter, Karoline Krause, Frank Siebenhaar, Martin Metz, Torsten Zuberbier, Denise Freier, Marcus Maurer
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 3 April 2020Source: Autoimmunity ReviewsAuthor(s): Dennis McGonagle, Kassem Sharif, Anthony O'Regan, Charlie Bridgewood
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
More News: Brain | Environmental Health | Epidemiology | Genetics | Men | Neurology | Neuroscience | Nutrition | Study