Chronic Obstructive Pulmonary Disease: A palliative medicine review of the disease, its therapies and drug interactions

Despite significant advances in treatment, chronic obstructive pulmonary disease (COPD) remains a chronic and progressive disease that frequently leads to premature mortality. COPD is associated with a constellation of significant symptoms including dyspnea, cough, wheezing, pain, fatigue, anxiety, depression and insomnia, and is associated with increased morbidity. Palliative care is appropriate to support these patients. However, historically palliative care has focused on supporting patients with malignant disease, rather than progressive chronic diseases such as COPD.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research

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Publication date: May 2020Source: Epilepsy &Behavior, Volume 106Author(s): Yanhong Yang, Mengyang Yang, Qianling Shi, Tiancheng Wang, Min Jiang
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Authors: Antoniu SA, Rajnoveanu R, Ulmeanu R, Mihaltan F, Grigore M Abstract Introduction: In chronic obstructive pulmonary disease (COPD), inhaled long-acting antimuscarinic agents (LAMA) are effective maintenance therapies used across all severity stages of the disease. Most of them are administered via dry powder inhalers, but these devices require a potent inspiratory flow which cannot be effectively achieved by patients with advanced disease. In such patients, inhaled therapy via nebulization might be an option.Areas covered: Revefenacin is a LAMA that was specifically formulated for once daily nebulization an...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
One of the biggest challenges of this unsettling time is the isolation we feel as we’re separated from friends and family, all the people for whom we care most deeply. But just being alone is only part of the difficulty. Our sense of remoteness is intensified by a pall of unease we can’t define: Loss and sorrow are also in the air. We fear losing—or we may have already lost—people we love. And when we work up the courage to look beyond our individual personal spheres, we see that many people who have made our world better, in big and small ways, have vanished before we were ready to let them go. But...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 feature remembrance Source Type: news
PMID: 32238125 [PubMed - as supplied by publisher]
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research
Abstract Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. T...
Source: An Acad Bras Cienc - Category: Science Authors: Tags: An Acad Bras Cienc Source Type: research
This report describes 2 cases of primary renal carcinoid tumor with unique presentations and management in our regional health care system. Because primary renal carcinoid tumors are quite uncommon, there are no clear established guidelines on preoperative imaging or posttreatment surveillance in patients with these tumors. There remains a large amount of variability in the diagnosis, workup, immunohistochemical analysis, treatment, and surveillance of patients with primary renal carcinoid tumors. As we learn more about this disease, we hope to optimize patient outcomes and standardize pretreatment workup and posttreatment...
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
DISCUSSION: Our case highlights how DIL should be on the differential when seemingly disparate symptoms develop in a patient receiving DIL-associated medications. Lupus is one of the "great imitators," in which symptoms can be ascribed to many different underlying causes. Although this patient's presentation may have been confounded by concomitant histoplasmosis, his improvement with cessation of hydralazine treatment argues in favor of DIL. His continued atypical serologic test results could be residual from his DIL and should normalize with time. However, it raises the question whether this bout of DIL has unma...
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
Publication date: Available online 3 April 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Katarzyna Mycroft, Rafal Krenke, Katarzyna Gorska
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
COVID-19 can cause a pneumonia-like lung infection, with a range of symptoms from mild or absent in some to life-threatening in others.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Dr Jeffrey Lieberman on how 'the worried well' and those with established mental illness can navigate this unprecedented moment.
Source: WebMD Health - Category: Consumer Health News Source Type: news
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